منابع مشابه
Diabetes and protein metabolism.
The celebrated Greek physician Aretaeus the Cappadocian some 1900 years ago described diabetes as a condition with “a melting down of the flesh and limbs into urine.” Remarkably, his observations are amazingly durable and accurate even by the standards of today with reference to type 1 diabetes. For example, insulin deprivation in type 1 diabetic patients causes a profound increase in catabolis...
متن کاملMitochondrial metabolism and diabetes
The oversupply of calories and sedentary lifestyle has resulted in a rapid increase of diabetes prevalence worldwide. During the past two decades, lines of evidence suggest that mitochondrial dysfunction plays a key role in the pathophysiology of diabetes. Mitochondria are vital to most of the eukaryotic cells as they provide energy in the form of adenosine triphosphate by oxidative phosphoryla...
متن کاملCarbohydrate Metabolism and Diabetes
after hydrolysis an additional quantity makes its appearance. He maintains that this phenomena is explained either by the presence of carbohydrate matter of lower cupric oxide power than glucose, or by the liberation of sugar from a glucoside. Proteid matter has recently been shown to be of a glucoside character, and to be able to yield cleavage carbohydrate. Forming a constituent part of a lar...
متن کاملProtein Metabolism in Diabetes Mellitus: Implications for Clinical Management
Diabetes mellitus is characterized by derangements in the metabolism not only of glucose and fat but also of protein (1). However, protein has always received less attention than fat and glucose, both in terms of alterations in its metabolism and in its nutritional implications. Although hyperglycemia and its consequences have always been the hallmark of the disease and plasma glucose the main ...
متن کاملInsulin resistance of protein metabolism in type 2 diabetes.
OBJECTIVE We previously demonstrated that 1) obesity impairs and 2) sex influences insulin sensitivity of protein metabolism, while 3) poor glycemic control in type 2 diabetes accelerates protein turnover in daily fed-fasted states. We hypothesized that type 2 diabetes alters the insulin sensitivity of protein metabolism and that sex modulates it. RESEARCH DESIGN AND METHODS Hyperinsulinemic ...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2007
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db07-1581